Résumé:
Pesticides are substances that meant to control pests includingall of the following
:herbicide,insecticides which may include termiticide , neonicotinoide the most common of
neonicotinoide is imidacloprid which is a systemique insecticide that acts as an insect neurotoxic. In
this study we were interested to know his impact on nephrotic function of wistar rats by usine two
defferent concentation 5 and 50 mg we used 12rats and devided them into 3 groups in each group
we put 4 rats then we had treated the first group by concentration 5 mg and the second group
with concentration50mg and we keep group as a control .our study is planned on many axes of
experimentation :study of blood paramter bichemical paramters oxidative stress paramters .
mitochondrial paramters .our result shown us at a concentration 50mg decrease in biochemical
paramters , increase in blood paramters, increase in metochondrial paramters (swilling and
permeability) decrease in GSH and MDAand GST level and increase in (CAT, GPX) levels and
at a concentration 5 mg our result sown us no changed in all paramter compared to control group
